Rethinking Prostate Cancer: The Role of Repurposed Drugs

When it comes to prostate cancer, men are often given two options: surgery or radiation. The path forward is presented as binary—intervene aggressively or risk progression. But this approach overlooks an entire realm of possibility that exists between doing nothing and doing everything. It also assumes all cancers behave the same, which we know is not true.

At Intellectual Medicine, we take a different approach—one grounded in medical research, clinical observation, and a deep respect for quality of life. Central to that philosophy is something called repurposed drug therapy.

What Is Repurposed Drug Therapy?

Repurposed drug therapy refers to the use of medications originally developed for one purpose, now used to fight cancer based on emerging evidence. These are not experimental or untested drugs—they are widely available, well-understood medications that, in the right combination, can help create an internal environment that is inhospitable to cancer progression.

I’ve spent years refining a protocol specifically designed for prostate cancer patients—particularly those who are not candidates for or have chosen to avoid aggressive intervention.

Which Medications Do I Use?

Each case is individualized, but the core program may include the following repurposed medications:

• Metformin – Originally for type 2 diabetes, Metformin may help lower insulin levels and reduce cellular fuel available to cancer cells.

• Sirolimus – An mTOR inhibitor with immune-modulating properties, showing potential in slowing cellular growth.

• Doxycycline – Beyond being an antibiotic, it may disrupt cancer cell metabolism and mitochondrial function.

• Naltrexone (Low Dose) – Known for modulating the immune system and supporting the body’s own anti-cancer defenses.

• Atorvastatin – A cholesterol-lowering drug that may also inhibit pathways involved in cancer growth.

• DMSA (Dimercaptosuccinic Acid) – Used in heavy metal detoxification, reducing environmental burdens that may impair immune function.

• Ivermectin – Investigated for its anti-parasitic effects and potential cancer-modulating properties.

• Mebendazole – Commonly used for parasites, with data suggesting anti-tumor potential.

• Viscum Mali (Mistletoe Therapy) – A natural agent widely used in integrative oncology in Europe.

• Testosterone (in select patients) – Contrary to popular belief, testosterone is not always contraindicated in prostate cancer. With proper monitoring, it can be part of a balanced approach.

Why It Matters

Many of these medications have decades of safety data behind them. They’re familiar, affordable, and often well tolerated. The synergy between these agents—when thoughtfully combined—can offer a form of defense without destroying the body in the process.

It’s not about rejecting conventional medicine. It’s about expanding the conversation and using every tool available to protect life, vitality, and dignity.

Who Is This For?

This approach is not for everyone. It’s best suited for:

• Men on active surveillance

• Men with early-stage cancer who want to avoid overtreatment

• Men with recurrent or advanced cancer seeking to complement their care

We don’t promise a cure. But we do promise thoughtful care, continuous monitoring, and a commitment to helping you make the most informed choices possible—without pressure.

If you’ve been told there’s only one way forward, I invite you to explore another path. One rooted in science, strategy, and strength.

— Dr. Stephen Petteruti
 Author of Fight Cancer Like a Man

Ready to Take the Next Step?

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Your next move doesn’t have to be radical—it just has to be strategic.